Emergency crews responded to a crash west of Steinbach late Thursday night.
Hanover Fire Chief Paul Wiebe says they were called to the intersection of Highway 52 and Road 32 East, between Steinbach and Mitchell, at approximately 11:15 pm.
Wiebe explains there were two vehicles involved and three occupants, all needing to be extricated.
A spokesperson for STARS, says a 37-year-old male patient was airlifted to Health Sciences Centre in Winnipeg in serious condition.
We are awaiting more details from RCMP on the extent of injuries to the other occupants.
Wiebe says the eastbound lanes were closed for several hours.
The scene was cleared at around 3 am.